How Well Do You Know NR Supplements? A Comprehensive Overview 

Today, is there anyone not pursuing well-being intertwined with longevity? At least not you and that’s why you’re reading this post! 

There are numerous supplements in the spotlight these days that promise to promote our health and healthy aging, and one of them is NR, Nicotinamide Riboside. NR, a typical form of Vitamin B3, is a potential compound that enhances our cellular functions, improves energy metabolism, and influences how we age. 

Essentially, NR supplementation boosts NAD+ levels, a coenzyme present in all living things, including human beings, and helps in DNA repair, regulating circadian rhythms, cell survival, energy production, and other biological processes. 

Here, we want to leave you with a comprehensive overview of NR supplements and their usefulness in our bodies, so read on! 

What’s Nicotinamide Riboside (NR)? 

If you’ve been looking for a compound to help with healthy aging and overall well-being benefits, you’ve come across NR. 

Also called Niagen, NR is a form of Vitamin B3 that helps body enzymes and cells perform various essential duties in the body. These processes include oxygen transport, disease prevention, food metabolism, and, most beneficially, healthy aging. 

In addition, NR is known to protect DNA and prevent the development of Alzheimer’s, among other brain fog disorders. 

NR can be found in various foods such as milk and meat or as an NR supplement, which are more crucially associated with longevity benefits because they are manufactured with NR chloride. 

Vitamin B3 and Nicotinamide Riboside – What’s the Difference? 

First, NR is a typical form of Vitamin B3, meaning Vitamin B3 is a spectrum of compounds that optimize body cellular processes, among which NR is a distinctive variant. 

The various forms of vitamin B3 contribute differently to the production of NAD+. Niacin, an imperative form of vitamin B3, can be taken as a supplement or in food. But it’s known to cause a flushing sensation, especially to new users and those who take high doses, making it less tolerable to some people. 

NR, on the other hand, has a metabolic pathway and unique structure that follows an enzymatic process for conversion to energy. The NRs are first transformed into noontide mononucleotide and finally into NAD+. 

Overview of Health Benefits of NR 

Pro tip: Always seek advice from your doctor before exercising regimen or supplementing your diet with NR compound, especially if you’re a pregnant woman, have other medications, or are nursing. 

NR health benefits include: 

  • Promotes cellular longevity 
  • Boosts NAD+ levels and mitochondrial health 
  • Reduces risks of cardiovascular health 
  • Helps in weight management 
  • Promotes muscle regeneration 
  • Mitigates risk of neurodegenerative disorders 
  • Promotes longevity 

Are there any Side Effects of NR? 

NR may not subject you to any serious side effects, especially if you take the right dosage and seek professional advice from your caregiver. However, there are often mild side effects that include headache, fatigue, nausea, diarrhea, etc. 

How Does NR Work? 

NR works in two distinct ways. First, it’s a natural booster of NAD+ or nicotinamide adenine dinucleotide, as shown in various studies involving animals. 

NAD+ levels often decline with age, necessitating the need for NR supplementation for cellular processes and energy metabolism to optimize. 

Second, NR helps activate sirtuin pathways in the body, which protect the human genome and improve DNA repair and longevity. 

Sources of Nicotinamide Riboside 

NR is a natural compound in certain foods, although in insufficient quantities to optimize the body processes, i.e., some food sources have small amounts of Nicotinamide Riboside contributing to the overall regimen. 

Some of the primary sources of NR include: 

Cow’s Milk 

Cow’s milk is a dominant source of natural NR in addition to protein. Taking it will often help in boosting NAD+ levels and subsequently enhance better cellular processes and healthy aging. 


Salmon, trout, sardines, tuna, and all other kinds of oily fish are rich in healthy fats and CoQ10, an essential that aids the conversion of food into energy after eating. 

Red Grapes 

Want a food rich in resveratrol and NR? Red grapes are an excellent resveratrol potent, so it helps with anti-inflammatory and antioxidant health benefits. Other health benefits that resveratrol can help include managing weight and promoting heart and brain health. 

Green Tea 

Green tea is a warming beverage sourced antioxidants and EGCG, Epigallocatechin gallate, a healthy compound that helps in managing eight, reducing inflammation. 


Although turmeric isn’t a rich source of NR, it contains curcumin, a necessary compound as an antioxidant and anti-inflammatory. That’s to say, turmeric provides similar health benefits to NR, and therefore, taking turmeric can be a natural way of NR supplementation. 


Here is an overview of NR covering everything from what it is, its health benefits, how it works, and its rich sources. With this information, you certainly can know how to get it and use it to avoid NR deficiency. NR deficiency can cause fatigue and low energy levels, oxidative stress, unhealthy weight gain, and difficulty sleeping.